Development of novel biophysical tools and methods to study and manipulate molecules on the surface of cells
Fig. 1. Schematic illustrations showing how the liquid flow through a small pipette can be used to (A) accumulate membrane-associated molecules by the hydrodynamic drag forces arising from the flow through the pipette and (B) to locally deliver molecules to subcellular areas.
1 Jönsson, P. et al. Proc. Natl. Acad. Sci. U.S.A.109:10328-10333 (2012).
2 Johansson, B. et al. Chem. Phys. Chem.15:486-491 (2014).
3 Babakinejad, B. and Jönsson, P. et al. Anal. Chem. 85:9333-9342 (2013).
4 Schobesberger, S. and Jönsson, P. et al. Biophys. J. 101:141-146 (2016).
People
Simon Davis (University of Oxford, UK), Viacheslav O. Nikolaev (University Medical Center Hamburg-Eppendorf, Germany), Julia Gorelik (Imperial College London, UK), Fredrik Höök (Chalmers, Sweden), Victoria Junghans, Peter Jönsson, David Klenerman (University of Cambridge, UK) and Yuri Korchev (Imperial College London, UK).
Funding
Swedish Research Council - project grant 2018