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Ulf Olsson. Portrait.

Ulf Olsson

Professor

Ulf Olsson. Portrait.

Influence of Salt on the Self-Assembly of Two Model Amyloid Heptapeptides

Author

  • V. Castelletto
  • I. W. Hamley
  • Celen Cenker
  • Ulf Olsson

Summary, in English

We study the effects of NaCl on the self-assembly of AAKLVFF and beta A beta AKLVFF in solution. Both AAKLVFF and beta A beta AKLVFF self-assemble into twisted fibers in aqueous solution. The addition of NaCl to aqueous solutions of AAKLVFF produces large crystal-like nanotapes which eventually precipitate. In contrast, highly twisted fibrils were observed for beta A beta AKLVFF solutions at low salt concentration, while a coexistence of highly twisted fibers and nanotubes was observed for beta A beta AKLVFF at high salt concentration. The self-assembled structures observed for beta A beta AKLVFF in NaCl solutions were ascribed to the progressive screening of the beta A beta AKLVFF surface charge caused by the addition of salt.

Department/s

  • Physical Chemistry

Publishing year

2010

Language

English

Pages

8002-8008

Publication/Series

The Journal of Physical Chemistry Part B

Volume

114

Issue

23

Document type

Article

Publisher

The American Chemical Society (ACS)

Topic

  • Physical Chemistry (including Surface- and Colloid Chemistry)

Status

Published

ISBN/ISSN/Other

  • ISSN: 1520-5207