Physical Chemistry

Lund University

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Controlled deposition of lipid liquid crystalline nanoparticles to obtain biofunctional surfaces

Investigation of non-lamellar nanoparticles formed by dispersion of self-assembled lipid liquid crystalline phases is stimulated by their many potential applications in science and technology; resulting from their unique solubilizing, encapsulating and space-dividing nature. Our aim is to control the interfacial behavior of lipid liquid crystalline nanoparticles (LCNPs) at surfaces to facilitate the exploitation of such systems for a number of potentially interesting uses, including preparation of functional surface coatings and uses as carriers of biologically active substances. We have shown that LCNPs can form well-defined layers at the solid-liquid interface with a structure and coverage that is determined by the interplay between self-assembly properties of the lipids and lipid surface interactions, respectively. Financed by Swedish Foundation for Strategic Research.

People: Tommy Nylander, Debby Chang, Fredrik Tiberg (Camurus AB), Justas Barauskas (Vilnius University).

Contact person: Tommy Nylander